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Conclusion: FOXO4-DRI promotes the nuclear export of phosphorylated P53 by inhibiting the binding of FOXO4 to P53 in endothelial cells, thereby facilitating the apoptosis of senescent endothelial cells and alleviating aging

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Third-party validation, including HPLC/MS testing where applicable, supports consistency, traceability, and reproducibility across controlled research applications

The American journal of cardiology

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