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Yes, B12 injections can have side effects, although they are generally rare and mild

Because peptides are naturally occurring and highly specific in their action, they carry minimal risk and are generally well-tolerated, with little to no side effects

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Those studies validate the general strategy of "needle, then deliver an active into the repair window," and GHK-Cu is a mechanistically sensible candidate for that slot, but readers should not mistake evidence for the strategy as evidence for this exact pairing