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The formulation chemistry, including buffers, preservatives, and stabilizers, can irritate surrounding tissue upon contact

10.1002/jcb.23166 126 ZhengY.WenQ.HuangY.GuoD

Phase I studies of the safety, tolerability, pharmacokinetics and pharmacodynamics of the dual glucagon receptor/glucagon-like peptide-1 receptor agonist BI 456906

Because it originates in the stomach, BPC-157 is highly stable and resistant to degradation, making it one of the most versatile and heavily researched peptides in the fields of sports medicine, longevity, and biohacking

Its not FDA-approved, and selling it as a drug or supplement in the US isnt legal (source)