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The reviewed studies also noted increased production of decorin, a proteoglycan that plays a role in collagen formation and wound healing

We recently found that targeting BET proteins induces glutamate dehydrogenase 1 (GDH1)-dependent glutamine metabolic remodeling in liver cancer, where glutamine-derived -KG through GDH1 maintains cancer cell survival when glycolysis is compromised 23 , but the underlying mechanisms are not fully understood

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This lack of dose standardization complicates direct comparisons and may contribute to the discrepancies in reported outcomes regarding physical development