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But it also does not mean the science is settled
We cover it fully in Does Tirzepatide Cause Hair Loss
Weight loss can include lean mass, especially if calorie intake drops without adequate protein and resistance training
The most commonly reported flu-like manifestations include: Nausea and general malaise the most frequent side effect, with incidence varying by product and dose (ranging from approximately 15-40% depending on the specific medication and dosage) Fatigue and low energy levels often described as feeling generally unwell or 'run down' Headaches ranging from mild to moderate intensity Dizziness or light-headedness particularly when standing up quickly, which may reflect dehydration or, in patients also taking insulin or sulfonylureas, possible hypoglycaemia Loss of appetite which, whilst therapeutically beneficial, can contribute to feeling unwell Mild gastrointestinal upset including occasional vomiting or abdominal discomfort These symptoms typically emerge because GLP-1 medications significantly alter gastrointestinal function and metabolic processes
The median percentage of heartburn-free days was 48% for patients treated with Phathoms drug, compared to 17% for placebo-treated participants
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