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Algunos pacientes pueden alcanzar sus objetivos teraputicos con dosis submximas y experimentar menos efectos secundarios, mientras que otros pueden requerir y tolerar dosis mximas para obtener beneficios ptimos

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Importantly, it does not typically drive insulin release under low-glucose conditions, reducing hypoglycemia risk in research settings

Furnari 2012)

Other important adverse effects include acute pancreatitis (presenting as severe, persistent abdominal pain radiating to the back), gallbladder disease , and acute kidney injury , particularly in the context of severe gastrointestinal side effects leading to dehydration