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Increase in rat brain glutathione following intracerebroventricular administration of -glutamylcysteine
NAD+ metabolism and interventions in premature renal aging and chronic kidney disease
The slides were mounted with a solution containing DAPI (Molecular Probes) and imaged using a Leica TCS SP8 laser scanning confocal microscope (Leica Microsystems CMS GmbH, Wetzlar, Germany)
However, despite the small amount needed, the effects of a deficiency can be devastating
The ratio of reduced to oxidized glutathione serves as a key indicator of the cellular redox potential, with even small changes in the GSH:GSSG ratio influencing protein function by altering cysteine oxidation and disulfide bond formation (Romero-Aristizabal et al., 2014)
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