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Pouring bacteriostatic water directly onto the lyophilized powder, rather than letting it stream gently down the vial wall, creates turbulence that can shear the peptide before it ever fully dissolves

A study performed by Yang and Wang in 2009 showed in-vivo study that pyridoxine can inhibit glutamate release from cerebrocortical synaptosomes by suppressing voltage-dependent Ca2+ entry

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