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Weight-loss treatments should be personalized
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Retatrutide exhibited a clear dose-dependent reduction in HbA1c, with the highest dose (12 mg) achieving a mean HbA1c reduction of 2.16 percentage points from baseline, compared to only 0.43% in the placebo groupan effect that was statistically highly significant
Moreover, heavy metals can deplete glutathione, a master intracellular antioxidant, by binding to thiol groups or interfering with glutathione synthesis and recycling (Ercal et al., 2001
Patients' clinical characteristics are presented in Table 1
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