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Notably, the GLP-1R agonist liraglutide suppressed exogenous lactate-induced upregulation of the acetyltransferase p300, which has been identified as a writer of histone lactylation by transferring the lactyl group from lactyl-CoA to specific histone lysine residues [16]

SchoenfeldJSibenallerZMapuskarKWagnerBCramer-MoralesKFurqanMet alO2 - and H2O2-mediated disruption of fe metabolism causes the differential susceptibility of NSCLC and GBM to pharmacological ascorbate

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