In the withdrawal trial, continuing preserved loss far better than switching to placebo, which regained about 14% over a year. The metabolic benefit fades in proportion to the weight regained, so a taper plus protein and resistance training beats a hard stop
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Low B12 in the body is also associated with having poor energy, frequent fatigue, and weakness
Glycemic control: In type 2 diabetes patients, HbA1c dropped by 1.32.0% (from ~8.0% to ~6.0%) with 412 mg doses [1]
Your genetics, stress levels, age, insulin sensitivity, and a variety of other factorscontrollable and notaffect your cravings, metabolism, and body composition