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J Endocrinol Invest (2017) 40(3):2817

This shift is supported by growing evidence that GLP-1s deliver multi-system benefits, from improved metabolic markers to reductions in cardiovascular risk, kidney disease progression, and other comorbidities common in people with type 2 diabetes or obesity

Yamazaki H, Kushiyama A, Sakoda H, Fujishiro M, Yamamotoya T, Nakatsu Y et al (2018) Protective effect of sex hormone-binding globulin against metabolic syndrome: in vitro evidence showing anti-inflammatory and lipolytic effects on adipocytes and macrophages

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Figure 1 illustrates the age and sex distribution of the patients with reported psychiatric adverse events