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Here is what the company's own published materials reveal
N Engl J Med 389(10):877888 Jastreboff AM, Kaplan LM, Fras JP et al (2023) Triple-Hormone-Receptor Agonist Retatrutide for Obesity - A Phase 2 Trial
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This means that whatever semaglutide is doing to the muscle proteome must be mediated indirectly through some other tissue signaling to muscle
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