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Leptin receptor-deficient db/db mice were purchased from the Jacksons Laboratory (Strain 000697)

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In a double-blind study with a placebo group, chronic insomniac patients administered with a DSIP analogue experienced a reduction in sleep latency by an average of 22 minutes, suggesting its potential as a therapeutic agent for severe chronic insomnia patients (Anderer & Saletu, 1991)