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Oral B12 supplements require intrinsic factor a glycoprotein produced in the stomach to be absorbed through the ileum
In addition, the ability of your body to absorb vitamin B12 from food can be hindered by certain medications, such as metformin, proton pump inhibitors, and antacids
People who are deficient in vitamin B12 are often prescribed B12 shots
While direct drug interactions are unlikely based on known mechanisms, the lack of safety studies and standardized formulations means healthcare providers cannot definitively assess safety or benefit
B12 injections are often given to people with a deficiency
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