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First approved as a once-weekly subcutaneous injection, semaglutide was considered an ideal peptide candidate for oral delivery with a permeation enhancer on account of its low molecular weight, long half-life, and high potency

In fact, most people who take semaglutide do experience side effects, but they are usually mild to moderate in severity

There is ongoing research on exploring their potential in cardiovascular diseases and neurodegenerative disorders, thereby, expanding their therapeutic applications beyond diabetes

See normally, a sugar called glucose is almost entirely absorbed in the small intestine so never makes it down to the colon