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The study therefore shows that during hypoglycaemia, glucagon counter-regulation is sustained during DPP-4 inhibition also in the elderly and that there seems to be a glucose threshold between 3.1 and 3.5 mmol/l for the relieve of the inhibition by DPP-4 inhibition of glucagon

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After the injection is made, it enters the bloodstream and causes an effect on relievers in the hypothalamus and pituitary gland

Prostaglandin E1 is a physiologically active substance with the expansion of blood vessels and inhibit platelet aggregation, and can inhibit vascular smooth muscle cells free Ca2 +, inhibite vascular sympathetic nerve endings, release norepinephrine for vascular smooth muscle relaxation, to decrease peripheral resistance , lower blood pressure, increase coronary blood flow, reduce myocardial oxygen consumption, thereby to relieve angina and reduce the incidence of myocardial infarction and reduced infarct size