Mild nausea is manageable through ginger tea, small sips of clear broth, or resting in an upright position for 30 minutes
Starting from t-12 led to positive AUC values
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Compared to wild-type BoNT/X protease, both X(PC2)b, an earlier evolutionary intermediate with activity on both VAMP1 and procaspase-1, and X(PC) demonstrated more stringent substrate requirements (Fig