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One review of seven studies showed that both methylcobalamin and a vitamin B-complex containing cyanocobalamin were effective in reducing symptoms of diabetic neuropathy, a complication of diabetes that leads to nerve damage ( Additionally, several animal studies have found that each form could have neuroprotective effects and may be beneficial in treating conditions that affect your nervous system ( SUMMARY Both methylcobalamin and cyanocobalamin can treat vitamin B12 deficiency
Polymorphisms in GLP-1 receptor genes, incretin pathway enzymes, and appetite regulation circuits influence individual response
The mechanism of action of ethanolamine ammonia-lyase, a B12-dependent enzyme: The reversible formation of 5-deoxyadenosine from adenosylcobalamin during the catalytic process
Journal of Hepatology 53 , 10851094, doi: 10.1016/j.jhep.2010.05.028 (2010)
Takeaways Acanthosis nigricans is a skin disorder that may happen in otherwise healthy people but often shows up in people with obesity, prediabetes, or diabetes
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