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NAD+ supplementation adds NAD+ from the outside
Claimed outcome NAD+ changes Evidence level Cell and animal evidence What research currently shows Blocking NNMT can preserve nicotinamide, a building block used to make NAD+
Results Body weight, fat mass, and cecal mass As expected, obese mice (maintained on an HFD followed by WD) had significantly higher body weights than mice continuously maintained on LD
Women who are pregnant, planning pregnancy, or breastfeeding should avoid the compound entirely due to unknown effects on fetal and infant development
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