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New peptide drugs are being developed for more effective treatments, with over 100 already approved by the FDA, highlighting their well-researched and regulated nature

Much of the current evidence is preclinical (cell and animal studies), and human data is still limited

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Caution is advised regarding the use of oral supplements in patients with pernicious anaemia, meaning that careful monitoring of symptoms would be required, and is not generally advised in patients with neurological symptoms, owing to limited efficacy and potentially serious impact of permanent neurological damage[25]