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Furthermore, PARP-1-mediated PARylation of KDM5B prevents the demethylation of H3K4me3, rendering the exclusion of H1 and the opening of chromatin

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Estrogens in male physiology

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[,] Inside the cell, cystine is transformed into cysteine, the rate-limiting component of the vital endogenous antioxidant molecule GSH

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Pentoxifylline, another vasodilator compound used as a possible treatment for NIHL, has been reported to have no beneficial effects in noise-exposed guinea pigs, even though it improved the blood supply to the cochlea when administered parenterally (Lamm and Arnold, 1999)

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