At least in my patient population, fibromyalgia does respond to a lot of things that I do, including GLP-1
They're usually injected and come with high price tags (up to $1,000/month) and a long list of potential side effects, from nausea and bloating to more serious risks like pancreatitis, bone-density loss, and even tumors
Melanotan 1 (MT1), also known as [Nle4, D-Phe7]-alpha-MSH or afamelanotide (CUV1647), is a synthetic analog of alpha-melanocyte-stimulating hormone (alpha-MSH) [1]
Despite these differences in baseline GLP-1 physiology, the mesolimbic reward system emerges as a critical convergence point across all three conditions
For the OSA indication after SURMOUNT-OSA, criteria are different: confirmed AHI of 15 or higher on polysomnography plus BMI of 30 or higher