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Many of the studies on oxalates focus on kidney stone formation, and these studies provide a clear picture of the interaction between oxalate homeostasis, kidney function, and calcium levels

Since humans cannot make vitamin C or store it in large amounts, it must be consumed regularly to prevent deficiency, ideally through fresh fruits and vegetables

Several other indications are under study, including obstructive sleep apnea, MASLD, knee osteoarthritis, chronic kidney disease, and cardiovascular outcomes

Through their activation of the cAMP-PKA pathway, they protect against oxidative stress and interfere with signalling of receptors for advanced glycation end products