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Despite their therapeutic promise, the clinical application of these natural agents has been hampered by pharmacokinetic challenges
Ortved KF, et al
Preclinical studies validate its multifactorial efficacy: facilitating endogenous neural stem cell differentiation in post-stroke recovery (Zhang et al., 2021), modulating pain signaling in inflammatory conditions (Zhang Q
Through the exosomeglialinflammation cascade, this mechanism facilitates the spread of focal neuronal injury to adjacent brain regions, thereby accelerating region-specific neurodegeneration and functional impairment in Alzheimers disease (Figure 3)
BPC-157 originates from a naturally occurring protein found in human gastric juice and is produced synthetically for research use
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