Therefore, in this review we detail the direct and indirect molecular mechanisms by which incretin receptor agonists inhibit fibrotic signalling pathways, and critically appraise the evidence for their preclinical and clinical efficacy in fibrotic disorders across diverse tissues, including the liver, heart, kidney, lung, and joints (Table 1
Less Common But Serious Side Effects Some rare but serious side effects need medical attention right away: Severe stomach pain that doesnt go away (could be pancreatitis) Allergic reactions Gallbladder problems Kidney issues Low blood sugar (if you also take diabetes medications) If you have any severe side effects, call your doctor right away
Non-fasting blood glucose and HbA1c levels were monitored at baseline and every three weeks
Those facts don't, on their own, independently verify treatment quality, individual eligibility, or outcomes
A patient could potentially benefit from combining hormonal therapy with GLP-1 treatment, addressing different aspects of the disease simultaneously