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If gallbladder disease is diagnosed, management depends on severity and may range from conservative observation for asymptomatic gallstones to cholecystectomy (surgical gallbladder removal) for acute cholecystitis or symptomatic cholelithiasis
The drug also showed potential for weight management, with no severe adverse events reported
The glucagon receptor mechanism appears to drive direct hepatic fat mobilisation independently of caloric restriction
The usual practical advice is simple: eat smaller meals, chew slowly, drink enough fluids, and increase fiber gradually if constipation appears
In less common cases, semaglutide may be linked to more serious side effects
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