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10.1038/sj.bjp.0704327 369

& Mancini, G.J

Multiple studies suggested that PCOS may further induce serious complications such as diabetes, hypertension, endometrial cancer (EC) and preeclampsia without timely intervention, which can severely affect the quality of life and long-term health outcomes of patients (Gilbert et al., 2018

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These trials revealed that empagliflozin-treated patients with left ventricular ejection fraction 40% experienced a lower risk of cardiovascular death or hospitalization for heart failure regardless of the presence or absence of diabetes [26, 27]