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Depicts MTHFR variant activity For example, an individual who is heterozygous at both C677T (C/T) and A1298C (A/C), known as a compound heterozygote, is expected to exhibit a 55% decrease in MTHFR enzymatic activity (35% activity due to the presence of one T allele at C677T and 20% activity due to the presence of one C allele at A1298C = 55%)

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Likewise, in the United Kingdom, the Medicines and Healthcare products Regulatory Agency (MHRA) has not authorized it for therapeutic use, highlighting the importance of regulatory processes in ensuring drug safety

The dose and frequency of treatment will depend on your health goals and the advice of your healthcare provider