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It further protects the skin from UV damage, reducing the risk of sun-induced hyperpigmentation

Neither spinalization nor bilateral transection of pelvic or dorsal penile nerves impaired the facilitator activity of intravenous Melanotan II, but removal of the lumbar paravertebral sympathetic chain abolished the effect, indicating recruitment of both central and peripheral melanocortin pathways depending on route of delivery

GLP-1 therapy does not change these screening recommendations

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Pinto M et al