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Many mechanisms of toxicity have been investigated, including oxidant stress, lipid peroxidation, mitochondrial dysfunction, and apoptosis through activation of the intrinsic pathway

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These medications have been shown to lead to significantly lower self-reported hunger, reduced food intake, and increased awareness around hunger cues and eating in response to environmental or emotional triggers

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With more of these doctor intensive appointments needed to complete treatment, the daily schedule can quickly be impacted, resulting in more stress on the practice