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79: 50921 Hagen TM, Liu J, Lykkesfeldt J, et al
Clinical trials suggest tirzepatide produces greater average weight loss (up to 22.5%) compared to semaglutide (up to 14.9%), though individual responses vary and both medications are considered highly effective
At that time, however, there were no clinical trials or peer-reviewed research studies to support the claims
Semaglutide patients lost a mean of 15.98 kg over 52 weeks, compared to 4.93 kg with dulaglutide (p=0.001)
Specifically, cell sorting of GST-EGFP-GPI DAF dramatically increased the positive ratio from 20% to 81% in K-562 cells and from 14% to 71% in Lenti-X 293T cells
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