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When applied topically, the concept of systemic GHK-Cu half life is less relevant
In a randomized, double-blind, placebo-controlled trial in 78 patients with progressive open-angle glaucoma (despite intraocular pressures of 18 mm Hg), use of citicoline eyedrops for three years blunted the decrease in retinal nerve fiber layer thickness compared to use of placebo eyedrops (91)
usage of other skin-lightening agents within one month prior to the study
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The chemistry that makes both AHK and GHK interesting is copper coordination
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