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Cryo-electron microscopy (Cryo-EM) has revealed that integrin v8 can bind to latent TGF- (L-TGF-) and activate TGF-/SMAD signaling without releasing TGF- from its latent complex, providing a novel perspective on pathway activation (Campbell et al
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Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans
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