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Keep in mind that unlike other anti-diabetic medications, Ozempic only assists the release of insulin when the stomach is full
Sometimes the scale will not budge for two weeks but your clothes will feel looser
65 In a meta-analysis by He et al, which included 76 RCTs covering more than 100,000 overweight or obese individuals, GLP-1 RA use was reported to increase the risk of gallbladder stones or biliary tract disease by 37% (RR 1.37 [95% CI 1.231.52])
The science of weight loss has fundamentally changed
Contact your GP if you experience: New or worsening symptoms suggesting thyroid dysfunction, such as extreme fatigue, significant unintended weight changes, palpitations, anxiety, or depression Persistent gastrointestinal side effects from GLP-1 medications that interfere with taking levothyroxine appropriately Neck swelling, pain, difficulty swallowing or persistent hoarseness , which could indicate thyroid changes requiring assessment, potentially via urgent suspected cancer pathways if concerning features are present Symptoms of hypoglycaemia (if you have diabetes), particularly if you take other glucose-lowering medications alongside GLP-1 therapy Severe, persistent abdominal pain (with or without vomiting), which could indicate pancreatitis requiring urgent medical attention Right upper abdominal pain, fever, or yellowing of the skin or eyes , which might suggest gallbladder problems, a known risk with GLP-1 medications and rapid weight loss New or worsening visual symptoms if you have diabetic retinopathy, as rapid improvement in blood glucose can sometimes temporarily worsen retinopathy [19] [20] Regular medication reviews are essential
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