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When administered as a once-weekly subcutaneous injection, Ozempic helps to: Stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner Suppress glucagon release , reducing hepatic glucose production Slow gastric emptying , which helps control post-meal blood sugar spikes Promote satiety , leading to reduced calorie intake and potential weight loss Ozempic treatment typically begins with a 0.25 mg weekly dose for 4 weeks, which is then increased to 0.5 mg weekly, with further titration to 1 mg if needed for glycaemic control

Through its projection neurons, the NTS relays integrated information to the hypothalamus and other forebrain regions, thereby coordinating feeding behaviour and associated physiological responses (48)

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Gasbjerg LS, Helsted MM, Hartmann B, Jensen MH, Gabe MBN, Sparre-Ulrich AH, Veedfald S, Stensen S, Lanng AR, Bergmann NC, et al