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Epithelial-mesenchymal transition in tumor metastasis

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Muftuoglu M, Li L, Mak DH, Burks JK, Xi Y, Hu B, Shaim H, Imahashi N, Bdaiwi MH, Jimenez JE, Banerjee PP, FLLW I, Kerbauy LN, Kaplan M, DePombo AM, Mendt MC, Basar R, Daher M, Marin D, Andreeff M , Wang J, Wierda WG, Thompson PA, Jain N, Keating MJ, Armstrong-James D, Champlin RE, Shpall EJ, Rezvani K

When miR-146a levels rise, two key TLR signaling proteins, IRAK1 and TRAF6, may decrease, and thus they may not transmit inflammatory signals inside the cell, including pathways linked to NF-B activation, which would otherwise play a major role in inflammatory signaling

Lipoic Acid Reduces the Activities of Biotin-Dependent Carboxylases in Rat Liver