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Additionally, in wild-type mice that overexpressed hHPN WT , there was a significant reduction in Cx32 expression, i.e., approximately 50 9% compared with both the AAV-hHPN RS and the vector-control (AAV-EGFP) groups (Fig
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Combination Potential Here's where things get interesting
Andrea Corona MapLight reports mixed results in Schizophrenia trial In their Phase 2 ZEPHR trial, MapLights novel oral drug for schizophrenia, the Ml/M4 muscarinic agonist ML-007C-MA, successfully hit its primary endpoint but only for the twice-daily version, not the once-daily dose