Yunus, S.R
This would be in line with preclinical observations that incretin receptor expression is down-regulated by exposure to high glucose, and improves once normoglycaemia is restored (48), and that dys-regulation of glycaemic control in otherwise healthy humans leads to impaired incretin actions (49)
Information should be available. Health Canada has told his company to restrict information on its website about conditions that certain drugs treat, even though American websites are not similarly limited, and anyone can find information with a quick Google search or from an AI assistant
Older adults (where sarcopenia compounds the effect), people starting with lower muscle mass, anyone eating very little protein, and those doing no resistance training
GLP-1s are actually simpler in many wayssubcutaneous injection, predictable titration schedule, manageable side effect profile (mostly GI: nausea, occasional vomiting)