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Both carry a boxed warning about thyroid C-cell tumors observed in rodents, although this has not been demonstrated in humans
2,3,4 Only in certain diseases, such as liver or kidney disease, should intake be monitored by a doctor
While commonly prescribed off-label (for an indication than what was approved by the FDA) as a weight loss drug, it is not FDA-approved for weight loss management
In the SUSTAIN-6 clinical trial, the incidence of pancreatic cancer was 0% and 0.1% with 0.5 mg and 1 mg semaglutide doses, respectively, compared to 0.2% with the placebo
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