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Methylcobalamin has an excellent safety profile with no established upper limit for toxicity

In a pilot trial involving patients with BAD, treatment with obeticholic acid successfully increased FGF19 levels, which led to the suppression of hepatic BA synthesis and resulted in a clinically significant reduction in stool weight (81)

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Typical protocols involve doses ranging from 13 mg daily or several times per week, often cycled in 812 week intervals with breaks to prevent receptor downregulation or potential copper accumulation

The timeline for recovery can vary, but it usually takes a few months for hair to start growing back