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Footnotes # Co-senior authors Abbreviations BRET Bioluminescence resonance energy transfer BSA Bovine serum albumin CyOFP Cyan-excitable orange fluorescent protein DERET Diffusion-enhanced resonance energy transfer FCS Fluorescence correlation spectroscopy FITC Fluorescein isothiocyanate GFP Green fluorescent protein GLP-1(R)(A) Glucagon-like peptide-1 (receptor) (agonist) GUV Giant unilameller vesicle MCD Methyl--cyclodextrin Nb37 Nanobody-37 POPC 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine T2D Type 2 diabetes TMR Tetramethylrhodamine TR-FRET Time-resolved Frster resonance energy transfer

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22.5% mean weight loss with FDA-approved 15mg tirzepatide over 72 weeks (directly applies to Ro-prescribed Zepbound): nejm.org/doi/full/10.1056/NEJMoa2206038 CDC Adult Obesity Facts (41.9% US prevalence per NHANES 2017March 2020): cdc.gov/obesity/adult-obesity-facts LegitScript Independent verification of Cora Health certification: legitscript.com/websites/?checker_keywords=trycora.io Pharmacy Compounding Accreditation Board (PCAB) accreditation framework for compounding pharmacies

Because glutathione is light-sensitive, we only expose our glutathione bags to light at the time of treatment to improve absorption and effectiveness

doi: 10.1016/j.jad.2019.02.063 36 CarruthersBJainADe MeirleirKPetersonDKlimasNLernerAet al