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Brechbuhl HM, Kachadourian R, Min E, Chan D, Day BJ

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Integrating evolutionary dynamics into treatment of metastatic castrate-resistant prostate cancer

In vitro and preclinical studies indicate that cagrilintide retains high potency across amylin and calcitonin receptor subtypes and demonstrates additive pharmacodynamic effects when combined with GLP-1 agonists like semaglutide (DAscanio et al