Endogenously, this occurs 612 times per day, with the largest pulses during slow-wave sleep
doi:10.2165/11538180-000000000-00000
Foundational Discovery Selective Senolytic Elimination in Aged Mice (Cell, 2017 Baar et al.) FOXO4-DRI Restores Fitness, Fur Density, Renal and Liver Function in Aged Mice The foundational study introducing FOXO4-DRI as a senolytic peptide was published in Cell by Baar and colleagues in 2017
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