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Patients with confirmed liver cirrhosis who had muscle cramps 4 times per month without other secondary etiologies for muscle cramps were evaluated for inclusion

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GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a tripeptide naturally present in human blood plasma at concentrations averaging 200 ng/mL at age 20, declining to approximately 80 ng/mL by age 60