Cagrilintide adds a separate fullness signal that retatrutide does not hit on its own
Individuals experiencing loose skin or stubborn fat pockets
GLP-1 also has a mild chronotropic effect, contributing 14 bpm on its own
Zepbound is approved by the Food and Drug Administration (FDA) for chronic weight management in adults with obesity (a body mass index, or BMI, of 30 or more) or adults who with overweight (BMI of 2730) and have at least one weight-related medical condition, such as high cholesterol or high blood pressure
For injectable GLP-1s, costs vary by medication type: compounded semaglutide costs $249/month, tirzepatide $349/month, brand-name options like Ozempic, Mounjaro, and Zepbound cost $1,399, and Wegovy costs $1,695