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For example, Ex-4 has been demonstrated to increase cardiac glucose uptake and ATP production by promoting GLUT1 translocation in H9c2 cells
However, noticeable weight loss takes time, as the body gradually adjusts
Not everyone experiences these side effects, and the people who do might not experience them to a significant degree
Between 40-82% of people experience gastrointestinal symptoms
For clinicians, the results could help guide medication choices when treating individuals with overlapping heart and metabolic disease
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