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The activation of these receptors in the hippocampus, a region crucial for memory formation, is believed to enhance synaptic plasticity and neurogenesis, providing a direct biological basis for the cognitive-enhancing effects observed in preclinical studies (During et al., 2003)
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Metabolic parameters were also assessed, and lipid metabolism had insignificant changes, whereas fasting insulin levels and HOMA-IR decreased significantly after IF compared with their baseline levels (32)
The cautions are the ones already covered
It does, however, mark one of the largest efforts so far to test a GLP-1 medication against alcohol addiction in a controlled clinical setting
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