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The general recommended dose of secukinumab for adult patients with HS is 300 mg subcutaneous injection with initial dosing at weeks 0, 1, 2, 3, and 4, followed by every 4 weeks maintenance dosing

In skin rejuvenation, it works by inhibiting tyrosinase, an enzyme responsible for melanin synthesis, leading to reduced hyperpigmentation and an even tone

Incorrect preparation of injectable peptides risks overdose, underdose, microbial contamination, injection-site infection, and anaphylaxis

The goal is steadier control, so healthy choices become more repeatable

Guidelines provided by KDIGO similarly recommend SGLT2i for people with an eGFR of 30 ml/min/1.73 m 2 due to the vascular and renal benefit, despite its modest effect on glucose control [2]