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The "LR3" designation refers to two key modifications: an N-terminal extension of 13 amino acids and a glutamate-to-arginine substitution at position 3
10.1074/jbc.M110.122721 66 IwanagaT.SatoM.MaedaT.OgiharaT.TamaiI
Ibuprofen, in particular, possesses Nf-kB inhibitory activity that may further help reducing excess inflammation/cytokine release in COVID-19 patients (Smart and Fawkes, 2020)
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